Afterwards, believing Samuel is going to kill him when he arrives, Dean visits Lisa and Ben to say goodbye but nearly drains Lisa and shoves Ben. Furious, Castiel tries to kill Crowley but discovers that he cannot. Castiel brought back Sam without his soul, and Dean implores the help of the in order to retrieve it. Castiel asks God for a sign to see if what he is doing is right or wrong, and says that if God doesn't answer him, he will do whatever it takes. The episode closes with Bobby lamenting Rufus and how they had never fully reconciled over a horrible mistake Bobby had made in the past, while the three remaining hunters bury Rufus.
To help persuade him, Sam introduces Dean to a new family led by their grandfather Samuel Mitch Pileggi. It fails because they had dog blood and Castiel appears full of power from having done the ritual himself. After a talk with her sister, Isabelle, Sam saves another guy that worked in the factory from getting killed and explained to him that he and a group of guys accidentally killed her because of a cruel joke they played on her. Dean asks him to trust him and stop what he is doing, because he's like a brother to him, but Castiel says he won't. Bobby sends Dean to Dr.
At one of the crime scenes, he discovers a baby that was left behind and calls Dean Jensen Ackles for help. He quickly discovers he isn't dealing with aliens but rather with fairies. Bobby begins to research Crowley's origins and even captures and tortures a to find Crowley's real name. Meanwhile, one of Castiel's lieutenants, Rachel, confronts Castiel about his plan to win the war and then tries to kill him. Sam makes her a deal: they will help her find Crowley if she promises to torture him for information about how to get Sam's soul back.
At one of the crime scenes, he discovers a baby that was left behind and calls Dean for help. Castiel observes Sam, Dean and Bobby while invisible, then saves them from demons, but a slip lets them know their suspicions are correct. Brenna frees Sam, who decapitates Dobbs. As Sam appears to have told the truth, they continue their hunt and discover it is the goddess of truth, who is invoking the spell. Boris confronts him, telling Dean that he has stopped nothing, but Dean kills him anyway. I'm knee-deep in half-eaten human hearts and exsanguinated ten year-old, and it's all making me.
Castiel betrays Crowley, who then allies himself with Raphael and performs the ritual to open the doors of Purgatory. Before Castiel is killed by Raphael, Balthazar returns and uses what appears to be a white crystal to disintegrate Raphael's host into salt apparently used on in when she looked back at the destruction of. While Sam is a bit reluctant to time travel, Dean is beside himself with excitement to return to the Wild, Wild West. Raphael flees the area when Castiel threatens him. Mouse over thumbnail for slideshow. The three head off to find the thief and come face to face with an old enemy. Giving up Ellie's Purgatory blood, Castiel escapes, while Crowley recites the spell to open Purgatory with Raphael.
Castiel kills the hybrids and spirits the men away. In the end Dean decides to live with Lisa and Ben, and tells Sam to keep in touch. Sam then begs for Castiel to be in his presence at which point Castiel shows up and tells Sam everything that has happened while he was soulless. Sam, Dean, Bobby, and Rufus all agree to electrocute each other to find out who is now infected with the worm. Sam flashes to earlier memories where he is helping Dean and Bobby look for Ellie Visyak, who has been taken by Castiel. Sam asks for help from Castiel, who is enraged that Crowley threatened Dean with his loved ones. But things don't go as planned as brothers are taken captive by Veritas and she is shocked to see that Sam is unaffected by her spell and he has been lying to Dean all along.
The spell affects Dean and he takes advantage of the situation to question Sam, but Sam says he just froze and is appalled Dean doesn't trust him. After a fight with two of the blood-suckers, Dean is bitten and turns into a vampire. The brothers are frustrated with Castiel's using them as a decoy, but Castiel is evasive in explaining himself and only says that he will tell them more later. To stop the Winchesters and , Castiel knocks down the mental barrier in Sam's mind. While Dean is acting as Death, Sam summons the angel Balthazar to learn how to prevent his soul from returning to his body.
A bartender helps him investigate his loss of memory. Crowley thinks the Winchesters are distracting Castiel, and tells him to kill them, but Castiel refuses, warning Crowley not to touch the brothers. They question the first victim's father, Brennan, a watchmaker who is adamant that his son will never return. It is later shown that the Arachne had not captured the men to feed, but to propagate the species, turning Dobbs and the other victims from a year ago into Arachnes as well, all of whom survived. However, before they can decide the baby's future, a shape-shifter breaks in and kidnaps the baby. Finally, Sam empties a rock salt shotgun shell onto the floor which forces the leprechaun to count each grain, and reads the spell to send all of them back to where they came from. Sam then leaves and burns the body, thinking the case is solved, although the worker he just saved is killed that same night.
Sam then tries to apologize to Brenna, but she does not wait to hear him. It is eventually discovered that Samuel is following Crowley's orders in exchange for the resurrection of his , Sam and Dean's mother. After talking to Lisa, Dean realizes that Lisa has been trying to forget him but he keeps appearing in her life and that she still has feelings for him. Continuing their research, Dean begins seeing a strange man only he can see and encounters a Tinkerbell-like radiating an energy sphere. The brothers become even more perplexed when Sam's investigation leads them to a world full of elves, gnomes and a leprechaun.